In the United States the leading cause of death is heart disease for both men and women. In every nation people suffer from heart disease, cancer, and diabetes, along with infectious diseases. However, throughout the past century life expectancy has increased tremendously. Younger generations are now having children later in life and older generations are living well into their 70’s and 80’s. Soon the world will have more older people than babies being born. Scientists have been searching for ways in which they can keep the elderly young at heart!
Recent studies have found that stem cells from young hearts can now help to rejuvenate aging hearts. This stem cell news is important in understanding how stem cells help different parts of the body, especially in helping the heart. Cedars-Sinai Heart Institute in Los Angeles, CA discovered that when injecting older rats with specialized stem cells from newborn rats the older rats were rejuvenated.
Old Hearts to Young Hearts
As you age your heart becomes stiffer, increasing the risk of heart failure. The researchers at Cedars-Sinai Heart Institute took cardiosphere-derived cells (CDCs) from infant rats that were bred in the laboratory. These cells were then injected into the hearts of older rats. A rat has the average life span of 2 years, so when injecting a 22-month-old rat with newborn cardiospheric cells the difference can be seen. There were two groups of rats: the control group and the group tested. Throughout the time of research the control group of rats was treated with saline. The rats given the placebo and the stem cells were then compared to young rats at the age of 4 months.
These rats were tested during stress tests, treadmill runs, and echocardiograms. When treated with the stem cells the older rats had longer telomeres in their heart cells. This is a sign that the older rats’ hearts are aging less rapidly than those given saline as the control. It was also noticeable that the older rats treated with stem cells increased in energy and exercise, as well as hair growth. Comparing the control group with the tested group showed clear signs of how stem cells can help the heart become more energized.
The stem cells used in the research were cardiosphere-derived cells that are immature and once mature specialize into one of three types of heart cells. These three types include: smooth muscle cells, cardiomyocytes, and endothelial cells. Smooth muscle cells are found in multiple organs such as the uterus, bladder, gastrointestinal tract and the heart. They are responsible for the contractions of these organs, in blood vessels they control the pressure and flow. Cardiomyocytes are the beating muscle cells that make up the atria and ventricles of your heart. These cells are responsible for the rhythmic beats of your heart. Endothelial cells form the lining of blood vessels and deliver oxygen to the cardiomyocytes. Each of these cells helps to increase energy.
While there’s still more research to be done on this to determine if this treatment can actually affect and increase lifespan. There is still more to be done on the age the donor must be and whether there is a specific age for the same rejuvenating effects. However, this treatment does show promise in treating heart failure. Throughout the past decade stem cell news has grown regarding what stem cells can do for the body. At Seattle Stem Cell Center we use your own stem cells to help rejuvenate your body.
Are you looking to better your health using your own body? Stem cells are the holistic approach to giving you a better quality of life. If you have any questions check out our FAQ page or us. We are here to help you and answer any questions you may have regarding how stem cells can better your body and your future. If you want to begin your stem cell procedure as soon as possible fill out the Health Intake Form.